ln this article are discussed the cultural aspects of lhe use of lnformation Technologies (IT) in organizations dedicated to academic research. The technology is analyzed as an integration element among the severa! knowledge areas existent in an organizalion andas a support resource to development and to the organization of the acquired and accumulated knowledge. The diff erences of the use of technology in each institution are analyzed, according to vision that each organizational culture has on what the human work is, the adapted form of relationship among the people. and the most usual form of work in that culture (individual or in group). The paper has a multi-methodological approach, using as data collection techniques the documental analysis, the personal interviews and a questiotmaire (electronic version and version in paper). lt concludes that the differences of use of the IT in the acaderruc research activity are associated to the relationship type that each institution maintains with the environment, to the predominant form of work in each organization (individual or in group), and to the nature of the activity (frontier research or research directed to the resolution of social problems) of each instfü1tion. lt was verified that the work form and the source of resources are lhe variables that best explains the diff erences of use of IT.